Clinical Research Trials
Principal Investigators Include: Moustafa Moustafa, MD
For more information please call (803) 531-2220 or email us at INFO@SCNEPHROLOGY.NET
| Company & Study name | Study Rationale | Study Candidates | Status |
|---|---|---|---|
| Merck Mk-2060: Prevention of Arteriovenous Graft Thrombosis in Patients With End Stage Renal Disease Receiving Hemodialysis | Phase 2 Clinical Outcome Trial to evaluate the efficacy and safety of two different doses of MK-2060 (a monoclonal antibody against Factor XI) in end stage renal disease (ESRD) participants receiving hemodialysis via an arteriovenous graft (AVG) |
Participants With End Stage Renal Disease Receiving Hemodialysis |
Active (Not Recruiting) |
AstraZenec/D9488C00001: Evaluate the Effect of Sodium Zirconium Cyclosilicate on Chronic Kidney Disease (CKD) Progression in Participants With CKD and Hyperkalaemia or at Risk of Hyperkalaemia |
A Phase 3, International, Randomised, Double-blind, Placebo-controlled Study to Evaluate the Effect of Sodium Zirconium Cyclosilicate on CKD Progression in Participants With CKD and Hyperkalaemia or at Risk of Hyperkalaemia https://www.clinicaltrials.gov/study/NCT05056727?term=D9488C00001&rank=1 |
Participants with CKD and hyperkalaemia or at risk of hyperkalaemia. |
Open (Recruiting) |
| Novo Nordisk, Inc./NN9535-4321: Effect of Semaglutide Versus Placebo on the Progression of Renal Impairment in Subjects With Type 2 Diabetes and Chronic Kidney Disease | Phase 3 study to see if semaglutide can slow down the growth and worsening of chronic kidney disease in people with type 2 diabetes. Participants will get the study medicine in a pen. Participants will use the pen to inject the medicine in a skin fold once a week. The total time participants will be in this study is about 3 to 5 years, but it could be longer. https://clinicaltrials.gov/study/NCT03819153?term=NN9535-4321&rank=1&page=1&limit=10 |
Participants With Type 2 Diabetes and Chronic Kidney Disease. |
Active (not recruting) |
Genentech Roche Cancer Screening Collection Study: A Data collection trial to further develop and evaluate content,methodology, specimen processing and quality control for test application in cancer screening. |
Roche Cancer Screening Collection Study is A Data collection trial to further develop and evaluate content, methodology, specimen processing and quality control for test application in cancer screening. Prospectively collecting peripheral blood samples, general medical record information including demographics and medical history as well as cancer screening outcomes and any cancer diagnosis confirmed during study participation. |
Participants who are eligible for routine lung cancer screening or routine CRC screening will be considered for participation in the study | Open (Recruiting) |
Kibow Biotech, Inc US-APR2020-01: To evaluate safety and efficacy of US-APR2020 in subjects with Chronic Kidney Disease Stage IV |
This is an Open-Label Rollover Extension Clinical Trial to Evaluate the Long-Term Safety and Efficacy of KT-301 (formerly US-APR2020) in Subjects With CKD IV Who Completed the US-APR2020-01 Study https://www.clinicaltrials.gov/study/NCT05407389?term=US-APR2020-01&rank=1&tab=table |
Participants with Chronic Kidney Disease (CKD) Stage IV |
Open (Recruiting) |
Vertex Pharmaceutical VX21-548-103 : Evaluation of Efficacy and Safety of VX-548 for Painful Diabetic Peripheral Neuropathy (DPN). |
A Phase 2, Randomized, Double-blind, Active-controlled, Dose-ranging, Parallel-design Study to evaluate the Efficacy and Safety of VX-548 in Subjects With Diagnosis of diabetes mellitus type 1 or type 2 and presence of bilateral pain in lower extremities due to Painful Diabetic Peripheral Neuropathy(DPN) for at least 1 year https://www.clinicaltrials.gov/study/NCT05660538?term=vx21-548-103&rank=1&tab=table |
Participants with Painful Diabetic Peripheral Neuropathy (DPN). | Open (Not Recruiting) |
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